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RNA-guided gene activation by CRISPR-Cas9-based transcription factors.
Nat Methods. 2013 Oct;10(10):973-6. doi: 10.1038/nmeth.2600. Epub 2013 Jul 25.
Nat Methods. 2013.
PMID: 23892895
Free PMC article.
Light-inducible gene regulation with engineered zinc finger proteins.
Polstein LR, Gersbach CA.
Polstein LR, et al.
Methods Mol Biol. 2014;1148:89-107. doi: 10.1007/978-1-4939-0470-9_7.
Methods Mol Biol. 2014.
PMID: 24718797
Free PMC article.
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A light-inducible CRISPR-Cas9 system for control of endogenous gene activation.
Polstein LR, Gersbach CA.
Polstein LR, et al.
Nat Chem Biol. 2015 Mar;11(3):198-200. doi: 10.1038/nchembio.1753. Epub 2015 Feb 9.
Nat Chem Biol. 2015.
PMID: 25664691
Free PMC article.
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An Engineered Optogenetic Switch for Spatiotemporal Control of Gene Expression, Cell Differentiation, and Tissue Morphogenesis.
Polstein LR, Juhas M, Hanna G, Bursac N, Gersbach CA.
Polstein LR, et al.
ACS Synth Biol. 2017 Nov 17;6(11):2003-2013. doi: 10.1021/acssynbio.7b00147. Epub 2017 Sep 6.
ACS Synth Biol. 2017.
PMID: 28793186
Free PMC article.
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Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators.
Polstein LR, Perez-Pinera P, Kocak DD, Vockley CM, Bledsoe P, Song L, Safi A, Crawford GE, Reddy TE, Gersbach CA.
Polstein LR, et al.
Genome Res. 2015 Aug;25(8):1158-69. doi: 10.1101/gr.179044.114. Epub 2015 May 29.
Genome Res. 2015.
PMID: 26025803
Free PMC article.
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Light-inducible spatiotemporal control of gene activation by customizable zinc finger transcription factors.
Polstein LR, Gersbach CA.
Polstein LR, et al.
J Am Chem Soc. 2012 Oct 10;134(40):16480-3. doi: 10.1021/ja3065667. Epub 2012 Sep 27.
J Am Chem Soc. 2012.
PMID: 22963237
Free PMC article.
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Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2.
Pathak GP, Spiltoir JI, Höglund C, Polstein LR, Heine-Koskinen S, Gersbach CA, Rossi J, Tucker CL.
Pathak GP, et al. Among authors: polstein lr.
Nucleic Acids Res. 2017 Nov 16;45(20):e167. doi: 10.1093/nar/gkx260.
Nucleic Acids Res. 2017.
PMID: 28431041
Free PMC article.
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